This article is a case. It is aimed at defining key problems of preventological work at the university. The article is designed as a phenomenological one using academic methods, questionnaires, interviews. Theoretical and topical coverage of the article includes international and Russian experience, suggestions can be approximated to the scope of CIS university education. As a result, the authors provide justification for the directions of preventological work at the university demonstrating the experience of its organization at the Ural Federal University. Further research should be directed at age and gender peculiarities, it is also possible to engage in more detailed research and analysis of international experience of organizing preventological work at international universities. University management practice can gain from formulating directions for organizing prevenological work. The value of the article is in applied use of obtained results: preventological work at the university should be cohesive and systematic.